Ran Lab

Developing NIRF imaging probes for various amyloid beta (Aβ) species in Alzheimer’s Disease

Selected Publications

Design, Synthesis, and Testing of Difluoroboron-Derivatized Curcumins as Near-Infrared Probes for in Vivo Detection of Amyloid-β Deposits

Oct 2009

Journal of the American Chemical Society

Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer’s disease

Nov 2013

Journal of the American Chemical Society

A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer’s disease

Aug 2014

Chemical Communications

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

Aug 2015

PNAS

Gut microbiota is critical for the induction of chemotherapy-induced pain

Jan 2017

Nature Neurosceince

Oxalate-curcumin–based probe for micro- and macroimaging of reactive oxygen species in Alzheimer’s disease

Nov 2017

PNAS

Turn-on chemiluminescence probes and dual-amplification of signal for detection of amyloid beta species in vivo

Aug 2020

Nature Communications

Molecularly generated light and its biomedical applications

Nov 2023

Angewandte Chemie International Edition in English

A Photolabile Curcumin-Diazirine Analogue Enables Phototherapy with Physically and Molecularly Produced Light for Alzheimer’s Disease Treatment

Nov 2023

Angewandte Chemie International Edition in English

In vivo three-dimensional brain imaging with chemiluminescence probes in Alzheimer’s disease models

Dec 2023

PNAS

Chongzhao Ran, PhD

Associate Professor of Radiology

Harvard Medical School

Investigator, Associate Professor (M)

Radiology, Mass General Research Institute

Mailing Address

Athinoula A. Martinos Center for Biomedical Imaging

CNY-Building #075

75 13th Street

Charlestown, MA 02129-2000

Contact Information

Email: cran@nmr.mgh.harvard.edu

Phone: 617-643-4886

Designed by Shiju (Michael) Gu: shgu@mgh.harvard.edu